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Atogepant

Catalogue number:
CAY35899-1 mg
Supplier:
Size:
1 mg
Product is available in:
  • UK
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£240.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1374248-81-3

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C29H23F6N5O3

Molecular Weight:

603.5

Alternative Names:

(3′s)-1′,2′,5,7-tetrahydro-n-[(3s,5s,6r)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-2′-oxo-spiro[6h-cyclopenta[b]pyridine-6,3′-[3h]pyrrolo[

Product Description:

A CGRP receptor antagonist (IC50 = 0.026 nM); selective for the CGRP receptor over the AM1 and AM2 receptors, CT receptor, and AMY1 and AMY3 receptors (IC50s = >18,000, 400, 6,274, 2.4 and 1,418 nM, respectively); increases the mechanical pain threshold in the von Frey test in a rat model of nitroglycerin-induced migraine at 3-30 mg/kg