A-769662
Catalogue number:
CAY11900-25 mg
Supplier:
Size:
25 mg
Product is available in:
£307.00
Estimated delivery Thu 9 Oct
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
844499-71-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C20H12N2O3S
Molecular Weight:
360.4
Alternative Names:
6,7-dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
Product Description:
A direct activator of AMPK (EC50 = 116 nM in a cell-free assay); allosterically activates AMPK and inhibits its dephosphorylation on Thr172; activates β1 subunit-containing AMPK heterotrimers; has been used to stimulate CYP450-mediated fatty acid oxidation, inhibit adipocyte differentiation, explore glucose uptake in skeletal muscle, and promote endothelial cell survival during metabolic stress