ML-SA5
Catalogue number:
CAY38326-10 mg
Supplier:
Size:
10 mg
Product is available in:
£331.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2418670-70-7
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C19H24ClN3O4S2
Molecular Weight:
458
Alternative Names:
n4-[3-chloro-2-
- MSDS: View or download
Product Description:
A TRPML1 agonist; activates whole-endolysosome IML1 in vacuolin-1-enlarged isolated vacuoles (EC50 = 333 nM); is cytotoxic to MeWo and M12 melanoma cells but not normal melanocytes at 3 µM; induces gastric acid secretion in isolated stomach from wild-type but not TRPML1-/- mice; decreases the necrotic area and percentage of centrally nucleated fibers in the dystrophin-deficient mdx mouse model of Duchenne muscular dystrophy at 2 and 5 mg/kg