AOH1996
Catalogue number:
CAY39526-5 mg
Supplier:
Size:
5 mg
Product is available in:
£105.00
Estimated delivery Wed 3 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2089314-64-5
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C26H22N2O4
Molecular Weight:
426.5
Alternative Names:
n-[2-[[2-(3-methoxyphenoxy)phenyl]amino]-2-oxoethyl]-1-naphthalenecarboxamide
Product Description:
An inhibitor of PCNA; binds to PCNA in a thermal shift assay; induces apoptosis in SK-N-DZ cells but not 7SMOO32 cells at 500 nM; induces DNA damage in wild-type RPB1- but not RPB1Y418A-expressing SK-N-AS cells; decreases tumor volume in SK-N-BE(2)-C neuroblastoma, MDA-MB-468 breast cancer, and NCI H82 small cell lung cancer mouse xenograft models at 40 mg/kg