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RN-1747

Catalogue number:
CAY37573-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£108.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1024448-59-6

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C17H18ClN3O4S

Molecular Weight:

395.9

Alternative Names:

1-[(4-chloro-2-nitrophenyl)sulfonyl]-4-(phenylmethyl)-piperazine

Product Description:

A TRPV4 agonist; selectively induces calcium influx in HEK293 cells expressing human, rat, or mouse TRPV4 (EC50s = 0.77, 4.1, and 4 µM, respectively) over HEK293 cells expressing human TRPV1, TRPV3, or TRPM8 (EC50s = >100, >30, and >30 µM, respectively); induces inward current in Xenopus oocytes expressing human TRPV4 at 10 µM; topical administration of RN-1747 induces hypothermia in rats