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Cucurbitacin IIa

Catalogue number:
CAY37371-1 mg
Supplier:
Size:
1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£85.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

58546-34-2

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C32H50O8

Molecular Weight:

562.7

Alternative Names:

(2β,3α,9β,10α,16α)-25-(acetyloxy)-2,3,16,20-tetrahydroxy-9-methyl-19-norlanost-5-ene-11,22-dione, dihydrocucurbitacin q1, hemslecin a

Product Description:

A triterpenoid with diverse biological activities; decreases the proliferation of HT-29 cells (IC50 = 370 nM); induces cell cycle arrest at the G2/M phase and apoptosis in HT-29 cells at 1 µM; induces cell cycle arrest at the G0/G1 phase in LPS-stimulated, but not unstimulated, RAW 264.7 macrophages at 2.5 µM; decreases immobility time in the forced swim test and the tail suspension test in a mouse model of intermittent unpredictable stress at 5 mg/kg