£37.00
Estimated delivery Wed 10 Jun
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
917837-54-8
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C19H15Cl2N3O2
Molecular Weight:
388.3
Alternative Names:
n-(4-chloro
Product Description:
A positive allosteric modulator of α7 nAChRs; enhances ACh-, nicotine-, or choline-induced currents in Xenopus oocytes expressing recombinant human α7 nAChRs (EC50s = 0.7, 0.6, and 0.5 µM, respectively); improves sensory gating deficits in a paired auditory stimulus paradigm in mice at 0.3 and 1 mg/kg; decreases the latency to find the platform in the Morris water maze test in a rat model of parasagittal fluid-percussion-induced TBI