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CHIR99021 (hydrochloride)

Catalogue number:
CAY39176-1 mg
Supplier:
Size:
1 mg
Product is available in:
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£36.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1797989-42-4

Purity:

≥95%

Formulation:

A solid

Molecular Formula:

C22H18Cl2N8 • HCl

Molecular Weight:

501.8

Alternative Names:

6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1h-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile, monohydrochloride, ct 99021

Product Description:

An aminopyrimidine derivative that inhibits GSK3α and GSK3β (IC50s = 10 and 6.7 nM, respectively); activates glycogen synthesis in CHO-IR cells (EC50 = 0.763 µM) and in isolated type 1 diabetic rat skeletal muscle; has been shown to promote self-renewal of embryonic stem cells