B-type Natriuretic Peptide, human recombinant, His Tag (rHuBNP)

Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 129 amino acids.