MMG-11
Catalogue number:
CAY38787-25 mg
Supplier:
Size:
25 mg
Product is available in:
£405.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
313254-94-3
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C15H14O7
Molecular Weight:
306.26746
Alternative Names:
5-[2-oxo-2-
Product Description:
An antagonist of TLR1/2 (IC50 = 0.9 µM in HEK-Blue cells expressing the human receptors); selective for TLR1/2 over the TLR2/6 heterodimer (IC50 = 7.4 µM in HEK-Blue cells expressing the human receptors); inhibits Pam3CKS4-induced TNF-α and IL-6 cytokine secretion in RAW 264.7 macrophages (IC50s = 3.3 and 0.2 µM, respectively); increases SERT and GSH activity, as well as decreases LDH activity and MDA levels, in M. avium-infected Caco-2 cells at 5 ng/ml