Hexachlorophene

• MSDS: View or download

An organochlorine antiseptic and antibacterial biocide; active against S. aureus (MIC = 1.56 µg/ml), E. faecium isolates from fresh produce (MICs = 5-50 mg/l), Salmonella isolates from meats (MICs = 2.5-25 mg/l), and Pseudomonas isolates from slaughterhouse surfaces (MICs = ≤0.0025-≤0.25 mg/l); inhibits infection of mouse astrocytoma DBT cells by recombinant MHV (IC50 = 1.2 µM); inhibits recombinant human glutathione transferases P1-1 and A3-3 (IC50s = 9.7 and v7 channels expressed in CHO cells (EC50 = 4.61 µM); toxic to fasted and non-fasted rats (LD50s = 215 and 165 mg/kg, respectively); reduces R. solani-induced fruit rot in cucumber plants when applied at 4.4 kg/ha