anti-Mast Cell Tryptase antibody [AA1]
ELISA, ICC/IF, IHC-Frozen sections, IHC-Formalin-fixed paraffin-embedded sections
Mouse
Mast Cell Tryptase
IgG1
Monoclonal
Human mast cell tryptase purified from human lung tissue.
tryptaseC; tryptaseB; Tryptase beta-2; TPS2; Tryptase II; EC 3.4.21.59; Tryptase-2; TPS1, TPS2, TPSB1
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Mouse Monoclonal antibody [AA1] recognizes Mast Cell TryptaseThis antibody recognizes human mast cell tryptase, both alpha and beta isoforms. Mouse anti Mast cel tryptase, clone AA1 is an excellent marker for mast cells, and does not bind to any other cell type in immunohistology (Walls et al. 1990).Tryptases are the products of a number of genes and form the major neutral protease present in mast cells secreted in response to infection and injury. Mast cell tryptase has an important role in the pathology of inflammatory diseases, especially asthma through bronchoconstriction (Zhang and Timmerman 1997).