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Lipid CL1

Catalogue number:
CAY38320-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£398.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1450888-71-7

Purity:

≥95%

Formulation:

A 25 mg/ml solution in ethanol

Molecular Formula:

C39H73NO2

Molecular Weight:

588

Alternative Names:

5-(dimethylamino)-pentanoic acid, (6z)-1,2-di-(4z)-4-decen-1-yl-6-dodecen-1-yl ester, lipid 10

Product Description:

An ionizable cationic trialkyl lipid; has been used in the formation of LNPs for delivering mRNA in vivo; LNPs containing lipid CL1 and encapsulating mRNA encoding human EPO increase blood EPO protein levels in mice; LNPs containing lipid CL1 and encapsulating mRNA encoding a reporter protein increase reporter expression in the liver in mice; LNPs containing lipid CL1 and encapsulating mRNA encoding influenza A HA increase serum anti-HA IgG antibody titers in a mouse model of HA vaccination