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Lipid 2,2(8,8) 4C CH3

Catalogue number:
CAY37910-1 mg
Supplier:
Size:
1 mg
Product is available in:
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£56.00 Estimated delivery Wed 10 Jun
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2230647-30-8

Purity:

≥95%

Formulation:

A solution in ethanol

Molecular Formula:

C37H70N2O5S

Molecular Weight:

655

Alternative Names:

heptadecan-9-yl (z)-n-(((4-(dimethylamino)butyl)thio)carbonyl)-n-(2-(non-2-en-1-yloxy)-2-oxoethyl)glycinate, atx-0114

Product Description:

An ionizable cationic lipid (pKa = 6.69); has been used in the generation of LNPs for the delivery of siRNA in vivo; LNPs containing lipid 2,2(8,8) 4C CH3 and encapsulating siRNA targeting Factor VII decrease plasma Factor VII protein levels by 90% in mice