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DSG-mPEG(2000)

Catalogue number:
CAY37800-1 g
Supplier:
Size:
1 g
Product is available in:
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£353.00 Estimated delivery Tue 12 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

308805-39-2

Purity:

≥95%

Formulation:

A solid

Molecular Formula:

(C2H4O)nC40H78O5

Molecular Weight:

386.1

Alternative Names:

α-[2,3-bis[(1-oxooctadecyl)oxy]propyl]-ω-methoxy-poly(oxy-1,2-ethanediyl), 1,2-distearoyl-rac-glycero-3-methylpolyoxyethylene

Product Description:

A PEGylated derivative of DSG; LNPs containing DSG-mPEG(2000) and encapsulating an imidazoquinoline TLR7 and TLR8 agonist and a peptide antigen each conjugated to PGA increase the activation of dendritic cells, macrophages, and B cells in the draining lymph node and dendritic cells and B cells in the spleen in mice compared to the non-LNP-encapsulated PGA-conjugated TLR7/8 agonist and peptide antigen.