TDI-10229
Catalogue number:
CAY37674-25 mg
Supplier:
Size:
25 mg
Product is available in:
£619.00
Estimated delivery Wed 20 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2810887-45-5
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C16H16ClN5
Molecular Weight:
313.78464
Alternative Names:
4-chloro-6-
Product Description:
A soluble adenylyl cyclase inhibitor (IC50 = 0.2 µM for the human enzyme in a cell-free assay); selective for sAC over AC1-3, -5, -8, and -9 at 10 µM; inhibits cAMP accumulation induced by IBMX in rodent sAC-expressing HEK293 cells (IC50 = 0.1 µM); inhibits capacitation-induced cAMP accumulation and PKA activation in isolated mouse and human sperm at 5 µM; prevents the acrosome reaction and fertilization of mouse sperm with mouse oocytes in vitro at 5 and 50 µM