CAS Number:
2645-32-1
Purity:
≥95% by HPLC.
Molecular Formula:
C7H5N5S2
Molecular Weight:
223.3
Alternative Names:
Thiocyanic acid, C,Cʹ-(2,6-diamino-3,5-pyridinediyl) ester
Product Description:
PR-619 is a non-selective, reversible inhibitor of deubiquitinases/deubiquitylases (DUBs) and ubiquitin-like isopeptidases. PR-619 inhibits many deubiquitinating enzymes in the 5-20 µM range. Additionally, PR-619 is cell permeable and treatment of cells results in the accumulation of both ubiquitin and sumo-conjugated proteins.