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TYK2 JH2 Pseudokinase Domain Inhibitor Screening Assay Kit

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Size:
384 reactions
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
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Alternative Names:

IMD35 assay, JTK1 assay kit, tyrosine kinase 2 kit, Non-receptor tyrosine-protein kinase biochemical assay kit

Product Description:

The TYK2 JH2 Pseudokinase Domain Inhibitor Screening Assay Kit is designed for screening and profiling small molecules that displace the fluorescently labeled probe (JH2 probe 1) from the JH2 domain of TYK2. The assay is based on the competition of the test compound with the JH2 probe for binding to purified TYK2 JH2. Using this kit, only one simple step on a microplate is required for screening. The JH2 probe 1 is incubated with a sample containing TYK2 JH2 to produce a change in fluorescent polarization that can then be measured using a fluorescence reader.