TNKS2 Homogenous Assay Kit
PARP5B, TANK2, TNKL, Poly [ADP-ribose] polymerase tankyrase-2, ADP-ribosyltransferase diphtheria toxin-like 6, ARTD6, Poly [ADP-ribose] polymerase 5B, Protein poly-ADP-ribosyltransferase tankyrase-2, TRF1-interacting ankyrin-related ADP-ribose polymerase
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The TNKS2 (also known as PARP5b) Homogeneous Assay Kit is designed to measure TNKS2 activity for screening and profiling applications. TNKS2 is known to catalyze the NAD-dependent addition of poly(ADP-ribose) to its substrate. The key to the TNKS2 Homogeneous Assay Kit is a highly specific antibody that recognizes PARylated substrate. With this kit, only three simple steps are required for TNKS2 reactions. First, a sample containing TNKS2 enzyme is incubated with biotinylated substrate and NAD for one hour. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.
