AG-270
Catalogue number:
CAY36246-5 mg
Supplier:
Size:
5 mg
Product is available in:
£312.00
Estimated delivery Tue 5 May
Shipping is calculated in checkout
Shipping is calculated in checkout
CAS Number:
2201056-66-6
Purity:
≥95%
Molecular Weight:
489.6
Alternative Names:
3-(1-cyclohexen-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(2-pyridinylamino)-pyrazolo[1,5-a]pyrimidin-7(4h)-one
Product Description:
A MAT2A inhibitor (IC50 = 0.014 µM); reduces SAM levels in and inhibits the proliferation of MTAP-null HCT116 cells (IC50s = 0.2 and 0.257 µM, respectively); reduces intratumor SAM levels and tumor growth in KP4 and HCT116 MTAP-null mouse xenograft models