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STM2457

Catalogue number:
CAY34280-25 mg
Supplier:
Size:
25 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£480.00 Estimated delivery Wed 15 Apr
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CAS Number:

2499663-01-1

Purity:

≥98%

Molecular Weight:

444.52906

Alternative Names:

n-[[6-[[(cyclohexylmethyl)amino]methyl]imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxo-4h-pyrido[1,2-a]pyrimidine-2-carboxamide

Product Description:

An inhibitor of the METTL3/14 complex (IC50 = 16.9 µM); inhibits growth in a panel of AML cell lines (IC50s = 0.6-10.3 µM); inhibits the proliferation, migration, and invasion of HuCC-T1 and HCCC-9810 ICC cells; increases survival in a PDX mouse model of AML at 50 mg/kg