£37.00
Estimated delivery Tue 12 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2259624-71-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C25H19ClF4N2O2
Molecular Weight:
490.876952
Alternative Names:
1-[(2-chloro-
Product Description:
A STING agonist; activates human wild-type STING (EC50 = 185 nM), as well as STING containing the polymorphisms R232, H232, or HAQ in HEK293 cells in an ISG54 luciferase reporter assay at 10 µM; induces the expression of IFN-α, IFN-β, TNF-α, CXCL10, IL-12p40, and IL-6 in isolated hMO-DCs at 10 µM; increases the expression of the dendritic cell markers CD83 and CD86 in hMO-DCs at 10 µM