MELK-8a (hydrochloride)
Catalogue number:
CAY37025-50 mg
Supplier:
Size:
50 mg
Product is available in:
£682.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2096992-20-8
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C25H32N6O • HCl
Molecular Weight:
469.02206
Alternative Names:
1-methyl-4-[4-[4-[3-(4-piperidinylmethoxy)-4-pyridinyl]-1h-pyrazol-1-yl]phenyl]-piperazine, monohydrochloride, nvs-melk8a
Product Description:
A MELK inhibitor (IC50 = 0.002 µM); selective for MELK over FLT3, haspin, KIT, and PDGFRα, (IC50s = 0.18, 0.19, >10, and 0.42 µM, respectively), as well as a panel of 456 kinases at 1 µM; inhibits the proliferation of MDA-MB-468 and MCF-7 cells (IC50s = 0.11 and 3.68 µM)