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Ferristatin II

Catalogue number:
CAY36621-100 g
Supplier:
Size:
100 g
Product is available in:
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£236.00 Estimated delivery Tue 23 Jun
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1937-37-7

Formulation:

A solid

Molecular Formula:

C34H25N9O7S2 • 2Na

Molecular Weight:

781.7303

Alternative Names:

4-amino-3-[2-[4′-[2-(2,4-diaminophenyl)diazenyl][1,1′-biphenyl]-4-yl]diazenyl]-5-hydroxy-6-(2-phenyldiazenyl)-2,7-naphthalenedisulfonic acid, disodium salt, c.i. 30235, chlorazol black, nsc 8679

Product Description:

An iron uptake inhibitor; inhibits iron uptake (IC50 = ~12 µM), as well as induces degradation of TfR1 in HeLa cells; reduces serum iron levels and transferrin saturation in rats at 0.2, 10, and 40 mg/kg; suppresses traumatic brain injury-induced lipid peroxidation, neuronal apoptosis, and the number of cortical iron deposits in rats