FB23-2
Catalogue number:
CAY36606-5 mg
Supplier:
Size:
5 mg
Product is available in:
£89.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2243736-45-8
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C18H15Cl2N3O3
Molecular Weight:
392.23552
Alternative Names:
2-[[2,6-di
Product Description:
An inhibitor of FTO (IC50 = 2.6 µM); reduces the proliferation of NB4 and Mono-Mac-6 cells (IC50s = 0.8 and 1.5 µM, respectively); increases m6A levels in isolated human bone marrow cells; suppresses the proliferation of isolated human bone marrow cells and a panel of AML cells (IC50s = 1.9-5.2 µM); delays disease onset and increases survival in a Mono-Mac-6 mouse xenograft model at 2 mg/kg