10-oxo-12(Z)-Octadecenoic Acid
Catalogue number:
CAY36977-500 ug
Supplier:
Size:
500 µg
Product is available in:
£466.00
Estimated delivery Thu 26 Mar
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
103521-29-5
Purity:
≥95%
Formulation:
A solution in ethanol
Molecular Formula:
C18H32O3
Molecular Weight:
296.5
Alternative Names:
10-keto-12z-octadecenoic acid, 10-oxo-12-cis-octadecenoic acid
Product Description:
A metabolite of linoleic acid and an activator of TRPV1; selectively increases calcium levels in HEK293 cells expressing TRPV1 over those expressing TRPV2, TRPV3, TRPV4, and TRPM8 at 100 µM; induces inward currents in HEK293 cells expressing TRPV1; dietary administration reduces weight gain and adipose tissue weight and increases the expression of Ucp1 in wild-type, but not Trpv1 knockout, mice fed a high-fat diet at 0.1% w/w