C12-200
Catalogue number:
CAY36699-10 mg
Supplier:
Size:
10 mg
Product is available in:
£133.00
Estimated delivery Tue 16 Sep
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1220890-25-4
Purity:
≥95%
Formulation:
A solution in ethanol
Molecular Formula:
C70H145N5O5
Molecular Weight:
1136.931
Alternative Names:
1,1′-[[2-[4-[2-[[2-[bis(2-hydroxydodecyl)amino]ethyl](2-hydroxydodecyl)amino]ethyl]-1-piperazinyl]ethyl]imino]bis-2-dodecanol
Product Description:
A branched-chain ionizable cationic lipidoid; has been used in combination with other lipids in the formation of LNPs for the delivery of mRNA, siRNA, or saRNA; LNPs containing C12-200 and encapsulating an mRNA reporter selectively accumulate in the liver, and to a lesser extent in the spleen and pancreas, in mice; administration of human EPO mRNA or factor VII siRNA in C12-200-containing LNPs increases serum EPO levels and reduces factor VII serum levels, respectively, in mice