www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

BRM/BRG1 ATP Inhibitor 1

Catalogue number:
CAY36138-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£772.00 Estimated delivery Tue 9 Jun
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2270879-17-7

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C11H9F3N4O2S

Molecular Weight:

318.276129

Alternative Names:

n-[3-(difluoromethyl)-5-isothiazolyl]-n′-[2-fluoro-5-(hydroxymethyl)-4-pyridinyl]-urea, brahma homologue/brahma-related gene 1 adenosine 5'-triphosphate inhibitor 1

Product Description:

A dual inhibitor of BRM and BRG1 ATPase activities (IC50s = <0.005 µM for both); reduces expression of KRT80 in H1299 and RERF-LC-A1 cell lines; reduces tumor cell growth in a RERF-LC-A1 lung cancer mouse xenograft model at 20mg/kg