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LSN2814617

Catalogue number:
CAY33607-10 mg
Supplier:
Size:
10 mg
Product is available in:
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£439.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1313498-08-6

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C18H20FN5O

Molecular Weight:

341.382903

Alternative Names:

3-(1,1-dimethylethyl)-7-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyridine

Product Description:

A positive allosteric modulator of mGluR5 receptors; potentiates glutamate-induced calcium mobilization in MCB3901 cells expressing human mGluR5 (EC50 = 52 nM); increases rat hippocampal mGluR5 receptor occupancy (ED50 = 13 mg/kg); increases wakefulness and decreases NREM and REM sleep in rats at 0.3, 1, and 3 mg/kg