www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Valproic Acid

Catalogue number:
CAY35739-50 g
Supplier:
Size:
50 g
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£269.00 Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

99-66-1

Purity:

≥95%

Formulation:

A neat liquid

Molecular Formula:

C8H16O2

Molecular Weight:

144.21144

Alternative Names:

2-propyl-pentanoic acid, 2-propylvaleric acid, nsc 93819, valproate, vpa

Product Description:

An analog of valeric acid; inhibits class I HDACs (IC50s = ~2 mM); decreases the number of axon branches in sensory neurons isolated from newborn rat dorsal root ganglia; inhibits amyloid-β deposition and neuritic plaque formation and decreases escape latency in the Morris water maze test in the APP23 transgenic mouse model of Alzheimer's disease; has anticonvulsant activity in the pentylenetetrazole seizure threshold test in mice (ED50 = 0.71 mmol/kg); induces neurotoxicity at ≥1.2 mmol/kg