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Loxoprofen (sodium salt)

Catalogue number:
CAY35088-1 g
Supplier:
Size:
1 g
Product is available in:
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£79.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

80382-23-6

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C15H18O3 • Na

Molecular Weight:

269.29139

Alternative Names:

α-methyl-4-[(2-oxocyclopentyl)methyl]-benzeneacetic acid, monosodium salt

Product Description:

An NSAID and a prodrug form of loxoprofen-SRS; inhibits COX-1 and COX-2 in isolated human whole blood (IC50s = 6.5 and 13.5 µM, respectively); reduces acetic acid-induced writhing in mice and carrageenan-induced paw edema and LPS-induced fever in rats (ED30s = 20.1, 0.7, and 2.79 mg/kg, respectively)