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Maduramicin

Catalogue number:
CAY20583-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
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  • Europe
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  • Rest of World
£522.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

79356-08-4

Purity:

≥85%

Formulation:

A solid

Molecular Formula:

C47H80O17

Molecular Weight:

917.1

Alternative Names:

(2r,3s,4s,5r,6s)-6-[(1r)-1-[(2s,5r,7s,8r,9s)-2-[(2s,2'r,3's,5r,5'r)-3'-[(2,6-dideoxy-3,4-di-o-methyl-β-l-arabino-hexopyranosyl)oxy]octahydro-2-methyl-5'-[(2s,3s,5r,6s)-tetrahydro-6-

Product Description:

A polyether ionophore antibiotic; selectively binds to monovalent cations over divalent cations; active against Gram-positive bacteria (MICs = 0.9-125 µg/ml); It reduces the viability of asexual and gametocyte P. falciparum parasites (EC50s = 1.3 and 14.8 nM, respectively); reduces P. berghei transmission in a mouse model of malaria at 4 and 8 mg/kg; reduces the severity of lesions and completely protects chicks against mortality in a model of E. tenella-induced coccidiosis at 5-10 ppm in the diet