Mofezolac
Catalogue number:
CAY34102-5 mg
Supplier:
Size:
5 mg
Product is available in:
£62.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
78967-07-4
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C19H17NO5
Molecular Weight:
339.34202
Alternative Names:
3,4-bis(4-
Product Description:
A COX-1 inhibitor (IC50 = 14 nM); selective for COX-1 over COX-2 (IC50 = 440 nM); protects against LPS-induced cell death in BV-2 microglia at 1 µg/ml; reduces hippocampal microglial activation and PGE2 production in a mouse model of LPS-induced neuroinflammation at 6 mg/kg; reduces phenylquinone-induced writhing in a mouse model of acute pain; dietary administration reduces the number of aberrant crypt foci and tumors in a rat model of beef tallow diet-induced colon carcinogenesis at 1,200 ppm