DL-threo-β-Hydroxyaspartic Acid
Catalogue number:
CAY35274-25 mg
Supplier:
Size:
25 mg
Product is available in:
£113.00
Estimated delivery Wed 17 Sep
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
4294-45-5
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C4H7NO5
Molecular Weight:
149.10212
Alternative Names:
rel-3r-hydroxy-d-aspartic acid, dl-tha, dl-threo-3-hydroxyaspartic acid
Product Description:
An EAAT inhibitor; inhibits glutamate uptake in COS-1 cells expressing human EAAT1 or EAAT2 (IC50s = 96 and 31 µM, respectively); inhibits inward currents induced by L-aspartate in EAAT4-expressing Xenopus oocytes (Ki = 0.6 µM) and by L-glutamate in EAAT5-expressing oocytes (Ki = 2.5 µM) voltage-clamped at -60 mV; intrathecal administration (7.5 and 15 µg/animal) reduces the number of flinches and shakes in the second phase of the formalin test in rats