MRTX-1133
Catalogue number:
CAY36413-1 mg
Supplier:
Size:
1 mg
Product is available in:
£69.00
Estimated delivery Fri 22 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2621928-55-8
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C33H31F3N6O2
Molecular Weight:
600.633689
Alternative Names:
4-[4-(3,8-
Product Description:
An inhibitor of K-RasG12D; selectively reduces ERK phosphorylation in AsPC-1 cells expressing mutant K-RasG12D (IC50 = 10.8 nM) over MiaPaCa-2 and SW620 cells expressing mutant K-RasG12C or K-RasG12V (IC50s = 456 and 4,400 nM, respectively) and MCF-7 cells expressing wild-type K-Ras in which ERK phosphorylation was not reduced