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3-Isomangostin

Catalogue number:
CAY36484-1 mg
Supplier:
Size:
1 mg
Product is available in:
  • UK
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£41.00 Estimated delivery Fri 9 Jan
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

19275-46-8

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C24H26O6

Molecular Weight:

410.45964

Alternative Names:

3,4-dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)-2h,6h-pyrano[3,2-b]xanthen-6-one

Product Description:

A xanthone with diverse biological activities; an inhibitor of MTH1 (IC50 = 52 nM); inhibits aldose reductase (IC50 = 3.48 µM), AChE (IC50 = 2.36 µg/ml), and BChE (IC50 = 5.32 µg/ml); inhibits the growth of P. falciparum strains D6 and W2 in isolated and infected red blood cells (IC50s = 3.23 and 2.52 µg/ml, respectively); inhibits cyclin D2/Cdk4 and cyclin E1/Cdk2 (EC50s = 15.6 and 34.92 µM, respectively) and reduces viability of HCC1937 and HCT116 cells (IC50s = 59.9 and 47.4 µM, respectively)