Oxotremorine (sesquifumarate)
Catalogue number:
CAY35707-500 mg
Supplier:
Size:
500 mg
Product is available in:
£237.00
Estimated delivery Tue 16 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
17360-35-9
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C12H18N2O • 3/2C4H4O4
Molecular Weight:
380.4
Alternative Names:
1-[4-(1-
Product Description:
A muscarinic acetylcholine receptor agonist; binds to M1, M2, M3, and M4 mAChRs (Kis = 3.31, 9.33, 5.24, and 7.08 µM, respectively, for the human receptors); inhibits ACh release in rat cerebral cortical slices at 10 µM, an effect that can be reversed by atropine; induces tremors, salivation, and lacrimation in mice (ED50s = 0.11, 0.22, and 0.28 mg/kg); induces analgesia in the hot plate test in mice at 0.5 mg/kg; has been used to induce parkinsonian symptoms as a model of Parkinson's disease in mice