Nipecotic Acid
Catalogue number:
CAY36126-250 mg
Supplier:
Size:
250 mg
Product is available in:
£94.00
Estimated delivery Thu 19 Feb
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
498-95-3
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C6H11NO2
Molecular Weight:
129.15708
Alternative Names:
3-piperidine
Product Description:
A GAT inhibitor (IC50s = 2.6, 310, 29, and 16 µM for mouse GAT-1, GAT-2, GAT-3, and GAT-4, respectively); does not bind GABAA or GABAB receptors (IC50s = >100 µM for both) but does bind the adenosine A3 receptor (IC50 = 0.01 µM); inhibits GABA uptake in isolated rabbit choroid plexus (IC50 = 244 µM); inhibits LDH release (EC50 = ~5 µM) and aggregation of htt-N63-148Q in PC12 cells; intraventricular administration (300 µg/animal) decreases tail flick reaction time in a rat model of morphine-induced analgesia