Maytansine
Catalogue number:
CAY36062-5 mg
Supplier:
Size:
5 mg
Product is available in:
£1055.00
Estimated delivery Tue 12 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
35846-53-8
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C34H46ClN3O10
Molecular Weight:
692.19596
Alternative Names:
maitansine, nsc 153858
Product Description:
An ansa macrolide with anticancer activity; inhibits the growth of L1210, L-5178-Y, and P388 murine leukemia cells (EC50s = 0.6, 12, and 1.5 nM, respectively); inhibits erythrocyte and brain tubulin polymerization at 20 µM; increases survival in a P388 murine leukemia model from 0.021-0.1 mg/kg; has also been used in the synthesis of cytotoxic payload moieties of ADCs