www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Cu-GTSM

Catalogue number:
CAY35455-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£133.00 Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

68341-14-0

Purity:

≥95%

Formulation:

A solid

Molecular Formula:

C6H10CuN6S2

Molecular Weight:

293.86204

Alternative Names:

(sp-4-2)-[[2,2′-(1,2-ethanediylidene)bis[n-methylhydrazinecarbothioamidato-κn2,κs]](2-)]-copper, copper-gtsm, cuii(gtsm)

Product Description:

A copper-containing compound; active against methicillin-sensitive and -resistant S. aureus clinical isolates (IC50s = 0.3-0.6 µM for all); inhibits the growth of SK-N-MC neuroepithelioma cells and MRC-5 fibroblasts (IC50s = 0.009 and 0.27 µM, respectively); induces ROS production in SK-N-MC cells at 5 µM; reduces tumor burden in the TRAMP model at 2.5 mg/kg; positron-emitting copper isotopes containing Cu-GTSM have been used in PET imaging applications for copper trafficking in the TASTPM transgenic mouse model of Alzheimer’s disease