Tirabrutinib (hydrochloride)
Catalogue number:
HY-15771A-1mL
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1439901-97-9
Purity:
99.43
Molecular Weight:
490.94
Alternative Names:
ONO-4059 (hydrochloride); GS-4059 (hydrochloride)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Tirabrutinib (ONO-4059) hydrochloride is an orally active Bruton’s Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib hydrochloride irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib hydrochloride can be used in studies of autoimmune diseases and hematological malignancies[1][2][3][4].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)