Ac2-26 (human) (ammonium salt)

Name: Ac2-26 (human) (ammonium salt)
Brand: Cayman Chemical
SKU: CBSKU_100941164
Price: 83 GBP
Availability: InStock

Catalogue number:

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CAY34429-1 mg

Supplier:

Cayman Chemical

Size:

1 mg

Product is available in:

Currency:
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£83.00

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Estimated delivery Wed 17 Dec
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Purity:

≥90%

Molecular Weight:

3107.46988

Alternative Names:

n-acetyl-l-alanyl-l-methionyl-l-valyl-l-seryl-l-α-glutamyl-l-phenylalanyl-l-leucyl-l-lysyl-l-glutaminyl-l-alanyl-l-tryptophyl-l-phenylalanyl-l-isoleucyl-l-α-glutamyl-l-asp

Product Description:

An annexin A1-mimetic peptide; binds to HEK293 cells expressing human FPR1 or FPR2 (EC50s = 1.4 and 1.8 µM, respectively, in a radioligand binding assay); inhibits PMN rolling over TNF-α-stimulated HUVECs at 10 and 30 µM; inhibits LPS-induced production of PGE2 and NO in rat microglial cells at 10 and 100 µg/ml; decreases pulmonary edema in a rat model of ventilator-induced ischemia-reperfusion injury at 0.5 and 1 mg/kg