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3,5-Diiodo-L-thyronine

Catalogue number:
CAY35212-500 mg
Supplier:
Size:
500 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£73.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1041-01-6

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C15H13I2NO4

Molecular Weight:

525.077

Alternative Names:

o-(4-hydroxyphenyl)-3,5-diiodo-l-tyrosine, 3,5-diiodothyronine, 3,5-t2, nsc 90469

Product Description:

A thyroid hormone metabolite; binds to TRα1, TRβ1, and TRβ2 (EC50s = 0.8, 0.79, and 0.1 µM, respectively, in cell-free assays); stimulates oxygen consumption in perfused livers isolated from rats with sodium iodide-induced hypothyroidism; reduces subcutaneous and epididymal fat mass, as well as decreases serum leptin and cholesterol levels, in high-fat diet-induced obese mice at 2.5 µg/g per day