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PAR2 (1-6) amide (human) (trifluoroacetate salt)

Catalogue number:
CAY35204-5 mg
Supplier:
Size:
5 mg
Product is available in:
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£88.00 Estimated delivery Thu 8 Jan
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CAS Number:

2379569-17-0

Purity:

≥95%

Molecular Weight:

614.77808

Alternative Names:

l-seryl-l-leucyl-l-isoleucylglycyl-l-lysyl-l-valinamide, trifluoroacetate salt, sligkv-nh2

Product Description:

A peptide agonist of PAR2; binds to NCTC 2544 cells expressing human PAR2 (Ki = 9.64 µM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50 = 0.075 µM); reduces colony formation of A549 cells at 100 µM; induces superoxide production and degranulation in isolated human eosinophils at 500 µM; induces tear secretion in rats at 5 µmol/kg when used in combination with amastatin