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Plitidepsin

Catalogue number:
CAY34053-500 ug
Supplier:
Size:
500 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£323.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

137219-37-5

Purity:

≥98%

Formulation:

A solution in acetonitrile

Molecular Formula:

C57H87N7O15

Molecular Weight:

1110.33886

Alternative Names:

n-[1-(1,2-dioxopropyl)-l-prolyl]-didemnin a, aplidin, dehydrodidemnin b

Product Description:

A depsipeptide with diverse biological activities; binds to eEF1A2 (Kd = 79 nM); inhibits proliferation of NCI H460 and HGC-27 cells (IC50s = 0.2 and 0.9 nM, respectively); inhibits bone resorption by osteoclasts in a pit formation assay using bovine bone slices at 0.01 nM; reduces viral titers and lung inflammation in the K18-hACE2 mouse model of SARS-CoV-2 infection at 0.3 mg/kg