Bufotalin
Catalogue number:
CAY34466-5 mg
Supplier:
Size:
5 mg
Product is available in:
£184.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
471-95-4
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C26H36O6
Molecular Weight:
444.56044
Alternative Names:
(3β,5β,16β)-
Product Description:
A bufadienolide with cytotoxic and immunomodulatory activities; induces cell cycle arrest at the G1 phase and apoptosis in Hep3B cells from 0.13-1.13 µM; reduces autoantibody production, serum levels of TNF-α, IL-1β, IFN-γ, IL-22, and IL-17, and the number of splenic and lymph node Th17 cells, as well as increases saliva flow rates in a mouse model of experimental Sjörgren’s syndrome at 100 µg/kg; induces lethality in anesthetized dogs (LD50 = 0.36 mg/kg)