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IDO-IN-2

Catalogue number:
CAY34876-1 mg
Supplier:
Size:
1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£46.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1668565-74-9

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C29H35N7O

Molecular Weight:

497.63478

Alternative Names:

n-[4-[bis(2-methylpropyl)amino]-2′-(2h-tetrazol-5-yl)[1,1′-biphenyl]-3-yl]-n′-(4-methylphenyl)-urea, pcc0208009

Product Description:

An IDO1 inhibitor (IC50 = 0.097 µM in HeLa cells); decreases intratumor levels of Ki67 and reduces tumor weight in a GL261 murine glioma heterotopic transplantation model at 100 mg/kg; decreases mechanical and thermal hypersensitivity, improves novel object recognition, and decreases ACC and amygdala levels of IDO1 in a rat model of SNL-induced neuropathic pain