This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2101700-15-4
Purity:
99.88
Molecular Weight:
479.43
Alternative Names:
LOXO-305
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Pirtobrutinib (LOXO-305), a highly selective and non-covalent next generation BTK inhibitor, inhibits diverse BTK C481 substitution mutations. Pirtobrutinib causes regression of BTK-dependent lymphoma tumors in mouse xenograft models. Pirtobrutinib is also more than 300-fold selective for BTK versus 370 other kinases tested and shows no significant inhibition of non-kinase off-targets at 1 µM[1].
Storage Temperature:
4°C (Powder, stored under nitrogen)