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K-975

Catalogue number:
HY-138565-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£249.00 Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2563855-03-6

Purity:

98.55

Molecular Weight:

287.74

Product Description:

K-975 is a potent, selective and orally active TEAD inhibitor, with a strong inhibitory effect against protein-protein interactions between YAP1/TAZ and TEAD. K-975 covalently binds to Cys359 located in the palmitate-binding pocket of TEAD via an acrylamide structure. K-975 exhibits antitumor activity on malignant pleural mesothelioma[1].

Storage Temperature:

-20°C, 3 years; 4°C, 2 years (Powder)

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