DLin-MC3-DMA
Catalogue number:
CAY34364-25 mg
Supplier:
Size:
25 mg
Product is available in:
£118.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1224606-06-7
Purity:
≥95%
Formulation:
A 100 mg/ml solution in ethanol
Molecular Formula:
C43H79NO2
Molecular Weight:
642.1
Alternative Names:
4-(dimethyl
Product Description:
An ionizable cationic lipid (apparent pKa = 6.44); has been used in the generation of lipid nanoparticles (LNPs) encapsulating siRNA, mRNA, or plasmid DNA for use in vitro and in vivo; LNPs containing DLin-MC3-DMA accumulate in the muscle and non-draining lymph nodes after intramuscular administration and in the spleen after intravenous administration in mice; LNPs containing DLin-MC3-DMA and encapsulating F7 siRNA reduce hepatic and plasma Factor VII levels in mice without inducing liver toxicity